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PI(3,5)P2 [early endosome membrane]
Stable Identifier
R-ALL-1806205
Type
Chemical Compound [SimpleEntity]
Compartment
early endosome membrane
Synonyms
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Phospholipid metabolism (Bos taurus)
PI Metabolism (Bos taurus)
Synthesis of PIPs at the early endosome membrane (Bos taurus)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Bos taurus)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Bos taurus)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Caenorhabditis elegans)
Metabolism of lipids (Caenorhabditis elegans)
Phospholipid metabolism (Caenorhabditis elegans)
PI Metabolism (Caenorhabditis elegans)
Synthesis of PIPs at the early endosome membrane (Caenorhabditis elegans)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Caenorhabditis elegans)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Caenorhabditis elegans)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Phospholipid metabolism (Canis familiaris)
PI Metabolism (Canis familiaris)
Synthesis of PIPs at the early endosome membrane (Canis familiaris)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Canis familiaris)
PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Canis familiaris)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Canis familiaris)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Danio rerio)
Metabolism of lipids (Danio rerio)
Phospholipid metabolism (Danio rerio)
PI Metabolism (Danio rerio)
Synthesis of PIPs at the early endosome membrane (Danio rerio)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Danio rerio)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Danio rerio)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Phospholipid metabolism (Dictyostelium discoideum)
PI Metabolism (Dictyostelium discoideum)
Synthesis of PIPs at the early endosome membrane (Dictyostelium discoideum)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Dictyostelium discoideum)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Dictyostelium discoideum)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Phospholipid metabolism (Drosophila melanogaster)
PI Metabolism (Drosophila melanogaster)
Synthesis of PIPs at the early endosome membrane (Drosophila melanogaster)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Drosophila melanogaster)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Drosophila melanogaster)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Phospholipid metabolism (Gallus gallus)
PI Metabolism (Gallus gallus)
Synthesis of PIPs at the early endosome membrane (Gallus gallus)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Gallus gallus)
PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Gallus gallus)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Gallus gallus)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
PIPs transport between early and late endosome membranes (Homo sapiens)
Presence of PI(3,5)P2 stimulates the maturation of the early endosome into the late endosome (Homo sapiens)
PI(3,5)P2 [early endosome membrane]
PIPs transport between early endosome and Golgi membranes (Homo sapiens)
PI(3,5)P2 transports from the early endosome membrane to the Golgi membrane (Homo sapiens)
PI(3,5)P2 [early endosome membrane]
Synthesis of PIPs at the early endosome membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Homo sapiens)
PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Homo sapiens)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Homo sapiens)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane (Homo sapiens)
PI(3,5)P2 [early endosome membrane]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Phospholipid metabolism (Mus musculus)
PI Metabolism (Mus musculus)
Synthesis of PIPs at the early endosome membrane (Mus musculus)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Mus musculus)
PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Mus musculus)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Mus musculus)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Plasmodium falciparum)
Metabolism of lipids (Plasmodium falciparum)
Phospholipid metabolism (Plasmodium falciparum)
PI Metabolism (Plasmodium falciparum)
Synthesis of PIPs at the early endosome membrane (Plasmodium falciparum)
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Plasmodium falciparum)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Phospholipid metabolism (Rattus norvegicus)
PI Metabolism (Rattus norvegicus)
Synthesis of PIPs at the early endosome membrane (Rattus norvegicus)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Rattus norvegicus)
PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Rattus norvegicus)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Rattus norvegicus)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Saccharomyces cerevisiae)
Metabolism of lipids (Saccharomyces cerevisiae)
Phospholipid metabolism (Saccharomyces cerevisiae)
PI Metabolism (Saccharomyces cerevisiae)
Synthesis of PIPs at the early endosome membrane (Saccharomyces cerevisiae)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Saccharomyces cerevisiae)
PI(3,5)P2 [early endosome membrane]
Metabolism (Schizosaccharomyces pombe)
Metabolism of lipids (Schizosaccharomyces pombe)
Phospholipid metabolism (Schizosaccharomyces pombe)
PI Metabolism (Schizosaccharomyces pombe)
Synthesis of PIPs at the early endosome membrane (Schizosaccharomyces pombe)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Schizosaccharomyces pombe)
PI(3,5)P2 [early endosome membrane]
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Phospholipid metabolism (Sus scrofa)
PI Metabolism (Sus scrofa)
Synthesis of PIPs at the early endosome membrane (Sus scrofa)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Sus scrofa)
PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Sus scrofa)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Sus scrofa)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Phospholipid metabolism (Xenopus tropicalis)
PI Metabolism (Xenopus tropicalis)
Synthesis of PIPs at the early endosome membrane (Xenopus tropicalis)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Xenopus tropicalis)
PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Xenopus tropicalis)
PI(3,5)P2 [early endosome membrane]
PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Xenopus tropicalis)
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
PI(3,5)P2 [early endosome membrane]
External Reference Information
External Reference
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [ChEBI:16851]
Participates
as a member of
PI5P, PI3P, PI(3,5)P2 [early endosome membrane]
as an input of
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Canis familiaris)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Gallus gallus)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Mus musculus)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Rattus norvegicus)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Sus scrofa)
PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Xenopus tropicalis)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Bos taurus)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Caenorhabditis elegans)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Canis familiaris)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Dictyostelium discoideum)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Drosophila melanogaster)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Danio rerio)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Gallus gallus)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Homo sapiens)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Mus musculus)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Rattus norvegicus)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Saccharomyces cerevisiae)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Schizosaccharomyces pombe)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Sus scrofa)
PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Xenopus tropicalis)
PI(3,5)P2 transports from the early endosome membrane to the Golgi membrane (Homo sapiens)
Presence of PI(3,5)P2 stimulates the maturation of the early endosome into the late endosome (Homo sapiens)
as an output of
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane (Homo sapiens)
PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the early endosome membrane (Mus musculus)
Other forms of this molecule
PI(3,5)P2 [phagophore assembly site membrane]
PI(3,5)P2 [plasma membrane]
PI(3,5)P2 [Golgi membrane]
PI(3,5)P2 [late endosome membrane]
PI(3,5)P2 [endoplasmic reticulum membrane]
PI(3,5)P2 [lysosomal membrane]
Cross References
COMPOUND
C11556
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